As a professional society dedicated to the effective and safe treatment of individuals with sexual dysfunction and men’s health overall, the International Society for Sexual Medicine is aware of recent concerns regarding cardiovascular risks associated with the use of testosterone therapy. This concern stems from two journal articles, one published in November 2013 in the Journal of the American Medical Association (1), and the other published in January 2014 in the journal, Plos One (2). Neither of these reports was a planned experimental study with control groups and defined goals. Instead these were retrospective analyses of data collected for other reasons. These types of analyses are prone to bias and error, and results are often irreproducible (3). For this reason, this type of study is generally not used for medical decision-making, although in some cases these may prompt further investigation with an experimental study.
Read more here: Testosterone Therapy and Cardiovascular Risks
Update: April 10, 2014 – In an unprecedented action, twenty-five international medical societies – including the ISSM – have petitioned the Journal of the American Medical Association to retract the article that precipitated recent concerns regarding cardiovascular risks with testosterone therapy, citing “gross data mismanagement” rendering the study “no longer credible.”